SeasonfiveofMurdochMysteriesopensinunfamiliarterritory,asDetectiveWilliamMurdoch(YannickBisson)leavesTorontototryhisluckwhiletheKlondikeGoldRushintheYukonwindsdown.Suspendedforinterferinginaninvestigation,ontherunforsurreptitiouslyfreeingamurderertomakeamends,andnursingabrokenheartafterDr.Ogden'smarriagetoanotherman,hetriestoescapehispast,andhispassionfordetectivework.Backinthecity,newlypromotedChiefConstableGiles(NigelBennett)makesitcleartoInspectorThomasBrackenreid(ThomasCraig),thathe'llbekeepingaverycloseeyeonpolicematters.Meanwhile,Murdoch'sbelovedformerassociate,Dr.JuliaOgden(HélèneJoy),isnowworkingalongsideActingDetectiveGeorgeCrabtree(JonnyHarris)andDr.EmilyGrace(GeorginaReilly),afeistyyoungprotégé.Intheremotenorth,Murdochispleasedtodiscoverthathisfledglingprospectingcareermaygarnergreatsuccess,asmallcomfortafterJulia'smarriagetoanotherman.Butashetriestorebuildhislife,hefindshimselfdrawnintothecaseofMrs.ElizabethBryant(JillHalfpenny),aninn